Adhering to Marxism as the guiding principle remains the fundamental hallmark of constructing China’s autonomous system of knowledge in the social sciences. The endeavor to build such a system not only aims to achieve the localization of social sciences but also pursues the sinicization of social science as an end in itself. While numerous scholars have made efforts in advancing the localization of social sciences and the instantiation of a sinicized social science，these endeavors have yet to fully meet the exigencies of accelerating the construction of China’s autonomous system of knowledge in the era. This deficiency stems are not only from the simplistic conflation of among practitioners but also from the relative neglect of the historical experiences and lessons of Marxism’s sinicization. Distinctively，serves merely as a starting point，whereas constitutes the ultimate direction and goal. In the new journey toward constructing China's autonomous system of knowledge，it is imperative to guide the effective elevation of under the leadership of Marxism while returning to the historical tradition of Marxism’s sinicization. Only through this integrated approach，the sinicization of social sciences and the instantiation of a sinicized social science can be realized effectively.鈥�