上海大学学报(自然科学版) ›› 2019, Vol. 25 ›› Issue (4): 597-603.doi: 10.12066/j.issn.1007-2861.1953

• 研究论文 • 上一篇    下一篇

激光诱导碳纳米笼对细菌的杀伤作用

韩春哲, 郭昱良, 陈杨, 桂馨()   

  1. 同济大学 生命科学与技术学院, 上海 200092
  • 收稿日期:2017-06-15 出版日期:2019-08-30 发布日期:2019-09-04
  • 通讯作者: 桂馨 E-mail:guixin@tongji.edu.cn
  • 基金资助:
    国家自然科学基金资助项目(31370961)

Killing bacteria effect of graphic carbon nanocages under laser irradiation

Chunzhe HAN, Yuliang GUO, Yang CHEN, Xin GUI()   

  1. School of Life Science and Technology, Tongji University, Shanghai 200092, China
  • Received:2017-06-15 Online:2019-08-30 Published:2019-09-04
  • Contact: Xin GUI E-mail:guixin@tongji.edu.cn

摘要:

以羰基铁为前驱体合成了由石墨壳层构成的石墨化碳纳米笼(graphic carbon nano- cages, GCNCs). 在671 nm激光照射下, 该GCNCs迅速将光能转化为热能. 0.1 mg/mL 的GCNCs在低功率密度的671 nm激光照射15 min的情况下, 可将大肠杆菌杀灭, 而单独激光照射不会影响细菌活性. 由于GCNCs的内部空腔可装载药物, 因此在多模式杀菌领域, GCNCs将会是一种性能优异的新型载体.

关键词: 碳纳米笼, 光热转化, 杀菌

Abstract:

Graphic carbon nanocages (GCNCs) are composed of graphite shells synthesized from carbonyl iron as precursors. The GCNCs could rapidly convert laser light energy to heat under 671 nm laser irradiation. $\textit{E. coli}$ incubated with 0.1 mg/mL of GCNCs were completely killed after 15 min of 671 nm laser irradiation, while the growth of $\textit{E. coli}$ was not affected by the GCNCs without laser irradiation. As GCNCs have huge internal cavity for loading drugs, these nanomaterials may be excellent carriers for multimodal bacteria killing.

Key words: graphic carbon (GCNCs), photothermal conversion, killing

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